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iPSC Differentiation Platform

Ricoh Biosciences employs a systematic, transcription factor-driven approach to generate functional cells from iPSCs with precision for research, screening and therapeutic development.

STAGE 1

Target Phenotype Definition

Define mature cell characteristics:

  • Transcriptomic profiles
  • Phenotypic markers
  • Functional assays
  • Customer endpoints
STAGE 2

Transcription Factor Selection

Eliminate trial-and-error approaches using the proprietary Human Gene Correlation Matrix to systematically test transcription factor combinations that guide cell lineage specifications.

STAGE 3

Culture

Optimization

Refine differentiation protocols:

  • Media formulations
  • Small molecule timing
  • Maturation parameters
  • Subtype specificity
STAGE 4

Cell Production & Delivery

Validated protocols scaled for manufacturing:

  • Cryopreservation
  • QC documentation
  • Ready-to-use delivery
  • Donor reproducibility

Our Core Technology

Our core technologies combine computational precision with biological insight to drive reproducible, clinically relevant outcomes.

Human Gene Correlation Matrix

Rapidly identify and select transcription factors for optimized differentiation based on our proprietary, large-scale transcriptomic database.

This multi-omic atlas lets us predict and validate transcription factor cocktails in silico, then confirm them at scale. Streamlining and accelerating the development of relevant cell lineages to power your program.

Human Gene Correlation Matrix

Quick-Tissueâ„¢ Differentiation Technology

Accelerate experimental timelines and increase throughput with our rapid, non-integrating differentiation technology.

Human Gene Correlation Matrix

From target validation to candidate screening, safety testing, and disease modeling, our platform accelerates every stage of the discovery pipeline. Quick-Tissueâ„¢ enables reproducible, non-integrating differentiation, producing high-quality human cells in days instead of weeks. This speed and reliability empower researchers to make faster, safer, and more confident decisions.

Applied Expertise

Decades of experience in a wide variety of downstream applications. 

At Ricoh Biosciences, we bring together decades of expertise across biotechnology, pharmaceuticals, data science, and translational research to help you move programs forward with confidence.

When you partner with us, you don’t just get a service provider, you gain an extension of your discovery and development team. Our scientists collaborate seamlessly with yours to:

  • Accelerate decision-making through data-driven experimental design and strategic scientific insight.
  • Reduce development risk via integrated project execution from concept through clinical translation.
  • Deliver reproducible, decision-ready data with innovative assay development, optimization, and advanced analytics.

From early discovery through clinical validation, Ricoh Biosciences helps you connect cutting-edge science to realy-world outcomes faster, smarter, and with greater confidence.

What Our Platform Enables

Advanced iPSC-based solutions for research, therapeutic development, and precision disease modeling, engineered to accelerate discovery and clinical translation.

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Custom iPSC Differentiation

Tailored differentiation protocols to convert iPSCs or ESCs into specific human cell types based on our proprietary transcription factor-based differentiation technology.

  • Compatible with any iPSC line, including patient-derived lines
  • Broad range of neuronal and glial cell types
  • Disease-relevant and functionally validated customization
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Novel Cell Type Development

Design and validation of entirely new differentiation routes for previously unavailable cell lineages and subtypes through systematic transcription factor discovery.

  • Optimal transcription factor identification
  • Custom medium formulation
  • Partnership-driven innovation
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Disease Modeling & Functional Assays

Integrated services combining patient-derived iPSC models with differentiation into disease-relevant cell types and comprehensive functional validation.

  • Patient-specific disease models and complex humanized systems
  • Multi-cell type disease panels and functional endpoint assays
  • Enables predictive, translational insights for drug discovery
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Cell Therapy Development

Scalable and robust pipeline for off-the-shelf allogeneic cell therapies designed for regenerative medicine and immune-based therapeutic applications.

  • Shorter manufacturing timelines through automation
  • Ready-to-use, universal donor iPSC-derived products
  • Clear clinical translation pathway from research to therapy
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Platform Benefits Overview

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From Idea to Insight, in Weeks.

Cut differentiation timelines dramatically to accelerate discovery.

Model Flexibility icon

Flexibility to Model What Matters Most.

Access rare or disease-relevant cell types on-demand.

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Reliable Insights You Can Trust.

Ensure reproducibility and consistency across studies.

Speak to a Scientist Today

Our expert team is here to help you unlock the full potential of Ricoh Biosciences’ platform. Whether you want to explore collaboration opportunities, learn about our technologies, or discuss your specific research needs, connect directly with a knowledgeable scientist who understands your challenges.

Online Marketplaces

Many scientists access our services through vetted platforms like ScienceExchange and Scientist.com, which ensures secure, compliant partnerships with trusted providers. Explore these options to find the most convenient way to work with us.

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Have a question about our products, services, or custom projects? Our team is here to help—reach out and we’ll get back to you as soon as possible.

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