Kickstart Your Research with iPSC Technology
Our transcription factor-based proprietary technology enables iPSC differentiation with a fast turnaround time to accelerate your research.
Let’s discuss how iPSC services can benefit your project.
Service Offerings
Partnering with Ricoh Biosciences gives you access to our robust portfolio of services. You can engage us directly for consultation. With Ricoh Biosciences, you have a reliable partner committed to accelerating your assay development, driving innovation in your research.
Custom iPSC Differentiation
Our custom iPSC differentiation service enables the generation of a wide range of human cell types—derived from both healthy and disease-specific iPSC lines. If you don’t currently have an iPSC line, we can also provide assistance in obtaining iPSC lines from iPSC banks or gene-editing service providers.
Consultations are free, so request a consultation today to discuss your project requirements. See here for some examples of iPSC lines we can help you acquire.
Disease Modeling
Utilizing our iPSC technology, we can generate disease-specific cell models that accurately recapitulate human disease conditions. This aids in advancing our understanding of disease pathophysiology and facilitates the development of potential therapeutic interventions.
Ricoh Biosciences helps you confirm disease-specific phenotypes when applicable right after differentiation.
Novel Cell-Type Development
Our team of experts can also assist in the development of new differentiation protocols using our proprietary Human Gene Expression Correlation Matrix and a library of hundreds of transcription factors, allowing you to generate specific cell types that are not readily available.
Ricoh Biosciences’ proprietary transcriptome database and plasmid library enable the systematic and fast iPSC differentiation protocol development. See how our technology works.
Custom Assay Services
Our Custom Assay Services allow you to outsource key phenotypic and functional assays using our iPSC-derived cells. Whether you’re validating disease phenotypes or assessing your drug activity, our experienced team can run the assays you need—saving you time, resources, and internal bandwidth.
We tailor each project to your research goals, providing high-quality, reproducible data using physiologically relevant human cell models.
Phenotypic Assays
We perform cell characterization studies to assess morphology, protein expression, and disease-relevant features using:
- High-content imaging analysis
- Quantitative gene or protein analysis (e.g., qPCR, ELISA)
Functional Assays
Functional assays provide insights into the biological behavior of your cells and their response to stimuli. Available options include:
-
Calcium oscillation imaging or electrophysiology (MEA) assays
- Target molecule detection (e.g., cytokines, neurotransmitters)
-
Metabolic activity and stress response
Let us handle the assay work so you can focus on interpreting results and moving your research forward. Request a free consultation to discuss your assay needs.
Work with Ricoh Biosciences
Partner with Ricoh Biosciences for expert services. Consult directly or use our marketplace for streamlined procurement. We accelerate assay development to drive research innovation.
Online Marketplaces
Streamline your R&D with Ricoh Biosciences’ profile on ScienceExchange or Scientist.com.
Our iPSC-derived technology differentiation kits are here to support your research. Partnering with these platforms guarantees efficient access to our innovations.
FAQ
Your Questions, Answered
Does Quick-Tissue™ technology leave a genetic footprint?
Sendai virus (SeV) is an RNA virus, so it does not integrate into the genomic DNA. In principle, a foreign gene introduced intracellularly in the form of RNA is quickly translated and expressed because, unlike DNA, RNA does not need to enter the nucleus for forced expression, thereby providing no chance of mutagenesis. This is discussed in the following review paper: Yamamoto, et al., (2009) “Current prospects for mRNA gene delivery.” Eur. J. Pharm Biopharm 71, 484-489.
Will SeV remain active after differentiation?
No. The SeV used in our kits is a temperature-sensitive mutant that is active at 33℃ but becomes inactive at 37℃, which is the temperature instructed in the user guides post-differentiation.
Is Sendai virus (SeV) dangerous?
SeV is not pathogenic to humans (i.e., humans are not the natural host of the virus) and the infection does not persist in immunocompetent animals. Furthermore, SeV used in our kits does not produce infectious viral particles upon transduction to host hPSCs and is a temperature-sensitive mutant, such that it is active at 33℃ but becomes inactive at 37℃. However, because SeV can be transmitted by aerosol and contact with respiratory secretions and is highly contagious, appropriate care must be taken to prevent potential mucosal exposure to the virus. Our SeV-based kits must be used under Biosafety Level 2 (BL-2) containment with a biological safety cabinet or a laminar flow hood and with appropriate personal protective equipment. In the event that the virus comes into contact with skin or eyes, decontaminate the affected area by flushing with plenty of water and follow the safety manual prepared by your laboratory and approved by your Institutional Biosafety Committee.
Do I need a license agreement for any of Ricoh Biosciences’ products?
No. You don’t need any licence or material transfer agreement (MTA) to use our differentiation kits or iPSC-derived cells. However, please be advised that these products are for research use only.
Contact Us
Have a question about our products, services, or custom projects? Our team is here to help—reach out and we’ll get back to you as soon as possible.
Subscribe
By signing up you are agreeing to our Privacy Policy