webinar
Using ALS Patient-Derived Motor Neurons to Study TDP-43 Mislocalization
⏰ 11:00 AM (EST)Â
👤 Vera Evanson, Ph.D. Â
🧬 ALS Disease Modeling Â
Event Overview
Amyotrophic lateral sclerosis (ALS) remains one of the most challenging neurodegenerative diseases to model. ALS patient-derived motor neurons offer a promising approach to studying disease-relevant biology, including key pathological features such as TDP-43 mislocalization.
In this webinar, Vera Evanson, Ph.D. discussed how ALS patient-derived motor neurons can be leveraged to interrogate TDP-43 mislocalization and associated cellular phenotypes in vitro. The presentation highlighted the use of physiologically relevant neuronal models to study disease mechanisms and pathological features of ALS.
Webinar Details
What You’ll Learn
- An overview of Ricoh Biosciences’ technology and how it enables the rapid generation of ALS patient-derived motor neurons.
- What TDP-43 is, how it is implicated in ALS, and why its mislocalization is a critical pathological feature.
- How these patient-derived motor neurons can be used to model TDP-43 mislocalization and related ALS-relevant phenotypes.
- How these models can be used to evaluate drug efficacy and TDP-43 modulation.
Ricoh Biosciences
Dr. Vera-Marie Evanson is an R&D Scientist at Ricoh Biosciences and a lead scientist on ALS assay development, working closely with partners to refine the company’s disease-modeling platform for translational research applications. She specializes in assay design, high-content imaging, and quantitative image analysis, with training from Radboud University and Johns Hopkins University.
Watch the Webinar
Interested in ALS disease modeling and discovery? View the webinar on-demand now to learn about ALS, TDP-43 mislocalization, and Ricoh Biosciences’ platform.