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Application Note

Generation of a Collection of CNS Cells from iPSCs by Quick-Tissue™ Technology

Review characterization data for eight hiPSC-derived CNS cell types — including excitatory, GABAergic, dopaminergic, motor, sensory, and cholinergic neurons plus astrocytes and microglia — generated using Quick-Tissue™ technology.

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Inside This Application Note

Review characterization data confirming subtype-specific marker expression across the full Quick-Neuron™ and Quick-Glia™ CNS cell portfolio.

  • Six neuronal subtypes (cholinergic, dopaminergic, excitatory, GABAergic, motor, sensory) generated in 7 days with lineage-specific marker expression confirmed by immunofluorescent staining and RNA-Seq analysis.
  • Quick-Glia™ astrocytes and microglia characterized for marker expression (GFAP, ALDH1L1, AQP4, EAAT1, CD49F, IBA1, TMEM119) and functional readouts including glutamate uptake, cytokine release, and phagocytosis
  • Functional characterization across cell types via MEA, patch clamp, calcium imaging, calcium flux, and neurotransmitter release assays